Now days, oral drug delivery of bilayer tablet are acquiring more acceptance among generic and brand product due to concourse of factors including advanced delivery strategies, combination therapy and patient compliance. This article provide an overview of bilayer matrix tablet technology, highlighting mainly hydrophilic matrix system of controlled release dosage form while providing a description of type of matrix system, their release mechanism and critical factor in the release of drug. Finally, a scheme for ELAN drug technology (DUREDAS™ Technology)’dual release drug delivery system of bilayer tablet manufacturing and selection of hydrophilic matrices is advised as a guideline to the formulation design and selection of process parameter.
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